- 1.
Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993; 362: 709 – 15.
- 2.
Lindahl T, Nyberg B. Rate of depurination of native deoxyribonucleic acid. Biochemistry 1972; 11: 3610 – 8.
- 3.
Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, Epe B et al. Accumulation of pre-mutagenic lesions in the DNA of mice defective in the removal of oxidative DNA base damage. Proc Natl Acad Sci USA 1999; 96: 13300 – 5.
- 4.
Woods CG. DNA repair disorders. Arch Dis Child 1998; 78: 178 – 84.
- 5.
Lindahl T, Karran P, Wood RD. DNA excision repair pathways. Curr Opin Genet Dev 1997; 7: 158 – 69.
- 6.
Krokan HE, Slupphaug G. DNA-reparasjonsenzymer og deres gener. Tidsskr Nor Lægeforen 1998; 118: 2037 – 43.
- 7.
Lindahl T, Wood RD. Quality control by DNA repair. Science 1999; 286: 189 – 95.
- 8.
Krokan HE, Nilsen H, Skorpen F, Otterlei M, Slupphaug G. Base excision repair of DNA in mammalian cells. FEBS Let 2000; 476: 73 – 7.
- 9.
Seeberg E, Eide L, Bjørås M. The base excision repair pathway. Trends Biochem Sci 1995; 20: 391 – 7.
- 10.
Kubota Y, Nash RA, Klungland A, Schär P, Barnes DE, Lindahl T. Reconstitution of the DNA base excision repair with purified human enzymes – interaction between DNA polymerase β and XRCCI. EMBO J 1996; 15: 6662 – 70.
- 11.
Klungland A, Höss M, Gunz D, Constantinou A, Clarkson SG, Bolton P et al. Base excision-repair of oxidative DNA damage activated by XPG protein. Mol Cell 1999; 3: 33 – 42.
- 12.
Klungland A, Lindahl T. Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J 1997; 16: 3341 – 8.
- 13.
De Boer J, Hoeijmakers JHJ. Nucleotide excision repair and human syndromes. Carcinogenesis 2000; 21: 453 – 60.
- 14.
Cleaver JE. Defective repair replication of DNA in xeroderma pigmentosum. Nature 1968; 218: 652 – 6.
- 15.
Aboussekhra A, Biggerstaff M, Shivji MK, Vilpo JA, Moncollin V, Podust VN et al. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 1995; 80: 859 – 68.
- 16.
Svejstrup JQ, Wang Z, Feaver WJ, Wu X, Bushnell DA, Donahue TF et al. Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 1995; 80: 21 – 8.
- 17.
Jiricny J. Mediating mismatch repair. Nature Genetics 2000; 24: 6 – 8.
- 18.
Ellis NA, German J. Molecular genetics of Bloom’s syndrome. Hum Mol Genet 1996; 5: 1457 – 63.
- 19.
Ellis NA, Groden J, Ye TZ, Straughen J, Lennon DJ, Ciocci S et al. The Bloom’s syndrome gene product is homologous to RecQ helicases. Cell 1995; 83: 655 – 66.
- 20.
Yu CE, Oshima J, Fu YH, Wijsman EM, Hisama F, Alisch R et al. Positional cloning of the Werner’s syndrome gene. Science 1996; 272: 258 – 62.
- 21.
Wilda M, Demuth I, Concannon P, Sperling K, Hameister H. Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development. Hum Mol Genet 2000; 9: 1739 – 44.
- 22.
Gatti RA, Berkel I, Boder E, Braedt G, Charmley P, Concannon P et al. Localization of an ataxia-telangiectasia gene to chromosome 11q22 – 23. Nature 1988; 336: 577 – 80.
- 23.
Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 1995; 268: 1749 – 53.
- 24.
Laake K, Ødegård A, Andersen TI, Bukholm IK, Karesen R, Nesland JM et al. Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM. Gen Chrom Canc 1997; 18: 175 – 80.
- 25.
Strathdee CA, Gavish H, Shannon WR, Buchwald M. Cloning of cDNAs for Fanconi’s anaemia by functional complementation. Nature 1992; 356: 763 – 7. (Published erratum 1992: 434.)
- 26.
Van Steeg H, Kraemer KH. Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer. Mol Med Today 1999; 5: 86 – 94.
- 27.
Wood RD. DNA repair in eucaryotes. Annu Rev Biochem 1996; 65: 135 – 67.
- 28.
Baynton K, Fuchs RPP. Lesions in DNA: hurdles for polymerases. Trends Biochem Sci 2000; 25: 74 – 9.
- 29.
Taylor EM, Broughton BC, Botta E, Stefanini M, Sarasin A, Jaspers NGJ et al. Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene. Proc Natl Acad Sci USA 1997; 94: 8658 – 63.
- 30.
Le Page F, Kwoh EE, Avrutskaya A, Gentil A, Leadon SA, Sarasin A et al. Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell 2000; 101: 159 – 71.
- 31.
Le Page F, Klungland A, Barnes DE, Sarasan A, Boiteux S. Transcription coupled repairof 8-oxoguanine in murine cells: The Ogg1 protein is required for repair in non transcribed sequences but not in transcribed sequences. Proc Natl Acad Sci USA 2000: 97: 8397 – 402.
- 32.
Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993; 75: 1027 – 38. (Published erratum 1994: 167.)
- 33.
Børresen-Dale A-L, Boman H. Arvelige kreftsykdommer. Tidsskr Nor Lægeforen 1988; 118: 1873 – 7.
- 34.
Andersson KB, Skålhegg BS. Genetisk skreddersøm av mus. Tidsskr Nor Lægeforen 1998; 118: 3952 – 7.
- 35.
Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A. Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53 and Brca2/p53 nullizygous embryos. Genes Dev 1997; 11: 1226 – 41.
- 36.
Chen M, Tomkins DJ, Auerbach W, McKerlie C, Youssoufian H, Liu L et al. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anemia. Nat Genet 1996; 12: 448 – 51.
- 37.
Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 1996; 12: 159 – 71.
- 38.
Wilson DM, Thompson LH. Life without DNA repair. Proc Natl Acad Sci USA 1997; 94: 12754 – 7.
- 39.
Friedberg EC, Meira LB. Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4. Mutat Res 2000; 459: 243 – 74.
- 40.
Bjørås M, Luna L, Johnsen B, Hoff E, Haug T, Rognes T et al. Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J 1997; 16: 6314 – 22.
- 41.
Roldan-Arjona T, Wei YF, Carter KC, Klungland A, Anselmino C, Wang RP et al. Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase. Proc Natl Acad Sci USA 1997; 94: 8016 – 20.
- 42.
Chevillard S, Radicella JP, Levalois C, Lebeau J, Poupon MF, Oudard S et al. Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours. Oncogene 1998; 16: 3083 – 6.
- 43.
Nilsen H, Rosewell I, Robins P, Skjelbred CF, Andersen S, Slupphaug G et al. UNG-deficient mice reveal a primary role of the uracil-DNA glycosylase enzyme during DNA replication. Mol Cell 2000; 5: 1059 – 65.
- 44.
Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51: 503 – 12.
- 45.
De Boer J, Donker I, de Wit J, Hoeijmakers JH, Weeda G. Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality. Cancer Res 1998; 58: 89 – 94.
- 46.
De Boer J, De Wit J, Visser P, Morreau H, Duran M, Hoeijmakers JHJ et al. A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy. Mol Cell 1998; 1: 981–90.
- 47.
Van der Horst GT, van Steeg H, Berg RJ, van Gool AJ, de Wit J, Weeda G et al. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 1997; 89: 425 – 35.
- 48.
Reitmar AH, Schmits R, Ewel A, Bapat B, Redston M, Mitri A et al. MSH2 deficient mice are viable and susceptible to lymphoid tumors. Nat Genet 1995; 11: 64 – 70.
- 49.
De Wind N, Dekker M, Berns A, Radman M, te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995; 82: 321 – 30.
- 50.
Edelmann W, Yang K, Umar A, Heyer J, Lau K, Fan K et al. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell 1997; 91: 467 – 77.
- 51.
Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S et al. Meiotic pachytene arrest in MLH1-deficient mice. Cell 1996; 85: 1125 – 34.
- 52.
Heyer J, Yang K, Lipkin M, Edelmann W, Kucherlapati R. Mouse models for colorectal cancer. Oncogene 1999; 18: 5325 – 33.
- 53.
Freudenreich CH, Kantrow SM, Zakian VA. Expansion and length-dependent fragility of CTG repeats in yeast. Science 1998; 279: 853 – 6.
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